Coiled-coil domain-containing protein 17 (CCDC17)

Homo sapiens — UniProt Q96LX7

Gene: CCDC17Homo sapiensSwissProt reviewed

About Coiled-coil domain-containing protein 17

Coiled-coil domain-containing protein 17 (CCDC17) is a protein from Homo sapiens identified by UniProt accession Q96LX7, 622 residues long. MolForge cross-references it against 0 known binders and 30 disease associations.

Target properties

Protein nameCoiled-coil domain-containing protein 17
UniProt accessionQ96LX7
GeneCCDC17
OrganismHomo sapiens
Length622 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (30)

Diseases linked to this target (Open Targets).

  • apolipoprotein A 1 measurement · score 0.28
  • body height · score 0.27
  • high density lipoprotein cholesterol measurement · score 0.25
  • platelet count · score 0.20
  • age-related hearing impairment · score 0.18
  • cortical surface area measurement · score 0.18
  • aspartate aminotransferase measurement · score 0.18
  • mean corpuscular volume · score 0.14
  • serum gamma-glutamyl transferase measurement · score 0.14
  • appendicular lean mass · score 0.13

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q96LX7-F1alphafoldPREDICTED67.88—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96LX7.

Amino-acid sequence (622 residues)

MDSHSGEPAL LPCGTCDMVF RSSALLATHT QRFCIGHPTQ EMTFGAQASV ATEPQRAAVV PQEHQGVPQE PQGLPDQQAS RSALKRLTEE VQWLRLSLQE MRPWITEVPR VFAGPWTRSE ARPQSPMSEA VGSPSERLRA LFRTRARRVA EMEAQSRALQ LRGEELSRRL QVVACTRGGM SRLFGLEQEI RELQAEAGRT RGALEVLGAR IQELQAEPGN PLSSRREAEL YSPVQKANPG TLAAEIRALR EAYIRDGGRD PGVLGQIWQL QVEASALELQ RSQTRRGRAG ATSGELPVVE AENRRLEAEI LALQMQRGRA PLGPQDLRLL GDASLQPKGR RDPPLLPPPV APPLPPLPGF SEPQLPGTMT RNLGLDSHFL LPTSDMLGPA PYDPGAGLVI FYDFLRGLEA SWIWVQLRTG LARDGRDTGR TTALPPALCL PPPPAPGPMG NCAILASRQP VPRLPPSSSV SLVCELQVWQ GLAWARAPQP KAWVSLGLFD QDQRVLSGRW RLPLRALPLD PSLSLGQLNG IPQAGQAELF LRLVNARDAA VQTLAEINPA SVHEYQYPPP VSSTSSLEAS FLTPAVGFAD PPPRTEEPLS GVKDRDEGLG PHHSSDLPPV SF

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Quick facts

UniProtQ96LX7
GeneCCDC17
OrganismHomo sapiens
Length622
Binders0
Diseases30
View on UniProt