Coiled-coil domain-containing protein 74B (CCDC74B)
Homo sapiens — UniProt Q96LY2
Data last refreshed: (UniProt release unknown)
Key facts
Coiled-coil domain-containing protein 74B (CCDC74B) is a protein from Homo sapiens identified by UniProt accession Q96LY2, 380 residues long. MolForge cross-references it against 0 known binders and 5 disease associations.
- UniProt accession: Q96LY2; gene symbol CCDC74B.
- Organism: Homo sapiens.
- Length: 380 amino acids.
- Top disease associations (Open Targets): blood protein measurement, breast carcinoma and chronic obstructive pulmonary disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Coiled-coil domain-containing protein 74B |
|---|---|
| UniProt accession | Q96LY2 |
| Gene | CCDC74B |
| Organism | Homo sapiens |
| Length | 380 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (5)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.02
- breast carcinoma · score 0.01
- chronic obstructive pulmonary disease · score 0.00
- lung disease · score 0.00
- Fibroadenoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96LY2-F1 | alphafold | PREDICTED | 59.19 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96LY2.
Amino-acid sequence (380 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CCDC74B?
The strongest Open Targets associations for CCDC74B are blood protein measurement, breast carcinoma, chronic obstructive pulmonary disease, lung disease and Fibroadenoma.
How long is the CCDC74B protein?
The Homo sapiens CCDC74B protein (UniProt Q96LY2) is 380 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96LY2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96LY2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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