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Regulator of microtubule dynamics protein 2 (RMDN2)

Homo sapiens — UniProt Q96LZ7

Gene: RMDN2Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Regulator of microtubule dynamics protein 2 (RMDN2) is a protein from Homo sapiens identified by UniProt accession Q96LZ7, 410 residues long. MolForge cross-references it against 0 known binders and 45 disease associations.

  • UniProt accession: Q96LZ7; gene symbol RMDN2.
  • Organism: Homo sapiens.
  • Length: 410 amino acids.
  • Top disease associations (Open Targets): eosinophil count, lean body mass and platelet count.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameRegulator of microtubule dynamics protein 2
UniProt accessionQ96LZ7
GeneRMDN2
OrganismHomo sapiens
Length410 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (45)

Diseases linked to this target (Open Targets).

  • eosinophil count · score 0.36
  • lean body mass · score 0.30
  • platelet count · score 0.29
  • mean platelet volume · score 0.29
  • diastolic blood pressure · score 0.28
  • vitamin D measurement · score 0.26
  • sitting height measurement · score 0.22
  • fat body mass · score 0.22
  • cutaneous melanoma · score 0.19
  • melanoma · score 0.17

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q96LZ7-F1alphafoldPREDICTED73.44—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96LZ7.

Amino-acid sequence (410 residues)

MPYSTNKELI LGIMVGTAGI SLLLLWYHKV RKPGIAMKLP EFLSLGNTFN SITLQDEIHD DQGTTVIFQE RQLQILEKLN ELLTNMEELK EEIRFLKEAI PKLEEYIQDE LGGKITVHKI SPQHRARKRR LPTIQSSATS NSSEEAESEG GYITANTDTE EQSFPVPKAF NTRVEELNLD VLLQKVDHLR MSESGKSESF ELLRDHKEKF RDEIEFMWRF ARAYGDMYEL STNTQEKKHY ANIGKTLSER AINRAPMNGH CHLWYAVLCG YVSEFEGLQN KINYGHLFKE HLDIAIKLLP EEPFLYYLKG RYCYTVSKLS WIEKKMAATL FGKIPSSTVQ EALHNFLKAE ELCPGYSNPN YMYLAKCYTD LEENQNALKF CNLALLLPTV TKEDKEAQKE MQKIMTSLKR

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with RMDN2?

The strongest Open Targets associations for RMDN2 are eosinophil count, lean body mass, platelet count, mean platelet volume and diastolic blood pressure.

How long is the RMDN2 protein?

The Homo sapiens RMDN2 protein (UniProt Q96LZ7) is 410 amino acids long.

Browse: Targets: R · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ96LZ7
GeneRMDN2
OrganismHomo sapiens
Length410
Binders0
Diseases45
View on UniProt