Melanoma-associated antigen B18 (MAGEB18)

About Melanoma-associated antigen B18

Melanoma-associated antigen B18 (MAGEB18) is a protein from Homo sapiens identified by UniProt accession Q96M61, 343 residues long. MolForge cross-references it against 0 known binders and 6 disease associations.

Target properties

Protein name	Melanoma-associated antigen B18
UniProt accession	Q96M61
Gene	MAGEB18
Organism	Homo sapiens
Length	343 residues
Molecular weight	—
EC numbers	—
Target class	—
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (6)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.33
pancreatic adenocarcinoma · score 0.04
glioblastoma multiforme · score 0.01
melanoma · score 0.01
sarcoma · score 0.00
Sjogren syndrome · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96M61-F1	alphafold	PREDICTED	73.98	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96M61.

Amino-acid sequence (343 residues)

MPRGQKSKLR AREKRHQARC ENQDLGATQA TVAEGESPSP AYLLFGDRPQ NLPAAETPSI PEALQGAPST TNAIAPVSCS SNEGASSQDE KSLGSSREAE GWKEDPLNKK VVSLVHFLLQ KYETKEPITK GDMIKFVIRK DKCHFNEILK RASEHMELAL GVDLKEVDPI RHYYAFFSKL DLTYDETTSD EEKIPKTGLL MIALGVIFLN GNRAPEEAVW EIMNMMGVYA DRKHFLYGDP RKVMTKDLVQ LKYLEYQQVP NSDPPRYEFL WGPRAHAETS KMKVLEFVAK IHDTVPSAFP SCYEEALRDE EQRTQARAAA RAHTAAMANA RSRTTSSSFS HAK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards