TLC domain-containing protein 4 (TLCD4)
Homo sapiens — UniProt Q96MV1
Data last refreshed: (UniProt release unknown)
Key facts
TLC domain-containing protein 4 (TLCD4) is a protein from Homo sapiens identified by UniProt accession Q96MV1, 263 residues long. MolForge cross-references it against 0 known binders and 57 disease associations.
- UniProt accession: Q96MV1; gene symbol TLCD4.
- Organism: Homo sapiens.
- Length: 263 amino acids.
- Top disease associations (Open Targets): bipolar disorder, schizophrenia and Tourette syndrome.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | TLC domain-containing protein 4 |
|---|---|
| UniProt accession | Q96MV1 |
| Gene | TLCD4 |
| Organism | Homo sapiens |
| Length | 263 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (57)
Diseases linked to this target (Open Targets).
- bipolar disorder · score 0.23
- schizophrenia · score 0.17
- Tourette syndrome · score 0.15
- platelet component distribution width · score 0.15
- alcohol consumption measurement · score 0.14
- lifestyle measurement · score 0.12
- fatty acid measurement · score 0.10
- motion sickness · score 0.10
- neutrophil count · score 0.09
- body mass index · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96MV1-F1 | alphafold | PREDICTED | 94.12 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96MV1.
Amino-acid sequence (263 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TLCD4?
The strongest Open Targets associations for TLCD4 are bipolar disorder, schizophrenia, Tourette syndrome, platelet component distribution width and alcohol consumption measurement.
How long is the TLCD4 protein?
The Homo sapiens TLCD4 protein (UniProt Q96MV1) is 263 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96MV1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96MV1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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