Ganglioside-induced differentiation-associated protein 1-like 1 (GDAP1L1)
Homo sapiens — UniProt Q96MZ0
Data last refreshed: (UniProt release unknown)
Key facts
Ganglioside-induced differentiation-associated protein 1-like 1 (GDAP1L1) is a protein from Homo sapiens identified by UniProt accession Q96MZ0, 367 residues long. MolForge cross-references it against 0 known binders and 23 disease associations.
- UniProt accession: Q96MZ0; gene symbol GDAP1L1.
- Organism: Homo sapiens.
- Length: 367 amino acids.
- Top disease associations (Open Targets): reticulocyte count, mean reticulocyte volume and type 2 diabetes mellitus.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ganglioside-induced differentiation-associated protein 1-like 1 |
|---|---|
| UniProt accession | Q96MZ0 |
| Gene | GDAP1L1 |
| Organism | Homo sapiens |
| Length | 367 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (23)
Diseases linked to this target (Open Targets).
- reticulocyte count · score 0.23
- mean reticulocyte volume · score 0.09
- type 2 diabetes mellitus · score 0.04
- mean corpuscular volume · score 0.03
- mean corpuscular hemoglobin · score 0.03
- vasculitis · score 0.03
- PHF-tau measurement · score 0.03
- high density lipoprotein cholesterol measurement · score 0.02
- lymphocyte:monocyte ratio · score 0.02
- appendicular lean mass · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96MZ0-F1 | alphafold | PREDICTED | 77.20 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96MZ0.
Amino-acid sequence (367 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with GDAP1L1?
The strongest Open Targets associations for GDAP1L1 are reticulocyte count, mean reticulocyte volume, type 2 diabetes mellitus, mean corpuscular volume and mean corpuscular hemoglobin.
How long is the GDAP1L1 protein?
The Homo sapiens GDAP1L1 protein (UniProt Q96MZ0) is 367 amino acids long.
Browse: Targets: G · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96MZ0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96MZ0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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