Ganglioside-induced differentiation-associated…

About Ganglioside-induced differentiation-associated protein 1-like 1

Ganglioside-induced differentiation-associated protein 1-like 1 (GDAP1L1) is a protein from Homo sapiens identified by UniProt accession Q96MZ0, 367 residues long. MolForge cross-references it against 0 known binders and 23 disease associations.

Target properties

Protein name	Ganglioside-induced differentiation-associated protein 1-like 1
UniProt accession	Q96MZ0
Gene	GDAP1L1
Organism	Homo sapiens
Length	367 residues
Molecular weight	—
EC numbers	—
Target class	—
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (23)

Diseases linked to this target (Open Targets).

reticulocyte count · score 0.23
mean reticulocyte volume · score 0.09
type 2 diabetes mellitus · score 0.04
mean corpuscular volume · score 0.03
mean corpuscular hemoglobin · score 0.03
vasculitis · score 0.03
PHF-tau measurement · score 0.03
high density lipoprotein cholesterol measurement · score 0.02
lymphocyte:monocyte ratio · score 0.02
appendicular lean mass · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96MZ0-F1	alphafold	PREDICTED	77.20	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96MZ0.

Amino-acid sequence (367 residues)

MATPNNLTPT NCSWWPISAL ESDAAKPAEA PDAPEAASPA HWPRESLVLY HWTQSFSSQK VRLVIAEKGL VCEERDVSLP QSEHKEPWFM RLNLGEEVPV IIHRDNIISD YDQIIDYVER TFTGEHVVAL MPEVGSLQHA RVLQYRELLD ALPMDAYTHG CILHPELTTD SMIPKYATAE IRRHLANATT DLMKLDHEEE PQLSEPYLSK QKKLMAKILE HDDVSYLKKI LGELAMVLDQ IEAELEKRKL ENEGQKCELW LCGCAFTLAD VLLGATLHRL KFLGLSKKYW EDGSRPNLQS FFERVQRRFA FRKVLGDIHT TLLSAVIPNA FRLVKRKPPS FFGASFLMGS LGGMGYFAYW YLKKKYI

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Ganglioside-induced differentiation-associated protein 1-like 1 (GDAP1L1)