AP-4 complex accessory subunit Tepsin (TEPSIN)
Homo sapiens — UniProt Q96N21
Data last refreshed: (UniProt release unknown)
Key facts
AP-4 complex accessory subunit Tepsin (TEPSIN) is a protein from Homo sapiens identified by UniProt accession Q96N21, 525 residues long. MolForge cross-references it against 0 known binders and 13 disease associations.
- UniProt accession: Q96N21; gene symbol TEPSIN.
- Organism: Homo sapiens.
- Length: 525 amino acids.
- Top disease associations (Open Targets): IgG fucosylation measurement, vitamin D measurement and age at menarche.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | AP-4 complex accessory subunit Tepsin |
|---|---|
| UniProt accession | Q96N21 |
| Gene | TEPSIN |
| Organism | Homo sapiens |
| Length | 525 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (13)
Diseases linked to this target (Open Targets).
- IgG fucosylation measurement · score 0.21
- vitamin D measurement · score 0.16
- age at menarche · score 0.13
- serum IgG glycosylation measurement · score 0.11
- IgG galactosylation measurement · score 0.07
- lymphocyte percentage of leukocytes · score 0.04
- triple-negative breast cancer · score 0.01
- hereditary spastic paraplegia · score 0.00
- embryonal carcinoma · score 0.00
- brain disease · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96N21-F1 | alphafold | PREDICTED | 67.78 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96N21.
Amino-acid sequence (525 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TEPSIN?
The strongest Open Targets associations for TEPSIN are IgG fucosylation measurement, vitamin D measurement, age at menarche, serum IgG glycosylation measurement and IgG galactosylation measurement.
How long is the TEPSIN protein?
The Homo sapiens TEPSIN protein (UniProt Q96N21) is 525 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96N21 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96N21 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.