RUN domain-containing protein 3B (RUNDC3B)
Homo sapiens — UniProt Q96NL0
Data last refreshed: (UniProt release unknown)
Key facts
RUN domain-containing protein 3B (RUNDC3B) is a protein from Homo sapiens identified by UniProt accession Q96NL0, 473 residues long. MolForge cross-references it against 0 known binders and 66 disease associations.
- UniProt accession: Q96NL0; gene symbol RUNDC3B.
- Organism: Homo sapiens.
- Length: 473 amino acids.
- Top disease associations (Open Targets): response to tramadol, blood protein measurement and schizophrenia.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | RUN domain-containing protein 3B |
|---|---|
| UniProt accession | Q96NL0 |
| Gene | RUNDC3B |
| Organism | Homo sapiens |
| Length | 473 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (66)
Diseases linked to this target (Open Targets).
- response to tramadol · score 0.53
- blood protein measurement · score 0.30
- schizophrenia · score 0.26
- leukocyte count · score 0.24
- neutrophil count · score 0.18
- cognitive decline measurement · score 0.16
- myeloid white cell count · score 0.11
- body height · score 0.09
- attention deficit hyperactivity disorder · score 0.05
- Tourette syndrome · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96NL0-F1 | alphafold | PREDICTED | 67.47 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96NL0.
Amino-acid sequence (473 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RUNDC3B?
The strongest Open Targets associations for RUNDC3B are response to tramadol, blood protein measurement, schizophrenia, leukocyte count and neutrophil count.
How long is the RUNDC3B protein?
The Homo sapiens RUNDC3B protein (UniProt Q96NL0) is 473 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96NL0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96NL0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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