Sodium channel and clathrin linker 1 (SCLT1)
Homo sapiens — UniProt Q96NL6
Data last refreshed: (UniProt release unknown)
Key facts
Sodium channel and clathrin linker 1 (SCLT1) is a protein from Homo sapiens identified by UniProt accession Q96NL6, 688 residues long. MolForge cross-references it against 0 known binders and 154 disease associations.
- UniProt accession: Q96NL6; gene symbol SCLT1.
- Organism: Homo sapiens.
- Length: 688 amino acids.
- Top disease associations (Open Targets): Astigmatism, Nystagmus and congenital hypothalamic hamartoma syndrome.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Sodium channel and clathrin linker 1 |
|---|---|
| UniProt accession | Q96NL6 |
| Gene | SCLT1 |
| Organism | Homo sapiens |
| Length | 688 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (154)
Diseases linked to this target (Open Targets).
- Astigmatism · score 0.41
- Nystagmus · score 0.41
- congenital hypothalamic hamartoma syndrome · score 0.41
- Hypermetropia · score 0.41
- Global developmental delay · score 0.41
- Bardet-Biedl syndrome · score 0.38
- hip bone mineral density · score 0.27
- hip bone size · score 0.26
- neurodegenerative disease · score 0.25
- fat body mass · score 0.21
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96NL6-F1 | alphafold | PREDICTED | 82.09 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96NL6.
Amino-acid sequence (688 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SCLT1?
The strongest Open Targets associations for SCLT1 are Astigmatism, Nystagmus, congenital hypothalamic hamartoma syndrome, Hypermetropia and Global developmental delay.
How long is the SCLT1 protein?
The Homo sapiens SCLT1 protein (UniProt Q96NL6) is 688 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96NL6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96NL6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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