Protein yippee-like 4 (YPEL4)
Homo sapiens — UniProt Q96NS1
Data last refreshed: (UniProt release unknown)
Key facts
Protein yippee-like 4 (YPEL4) is a protein from Homo sapiens identified by UniProt accession Q96NS1, 127 residues long. MolForge cross-references it against 0 known binders and 48 disease associations.
- UniProt accession: Q96NS1; gene symbol YPEL4.
- Organism: Homo sapiens.
- Length: 127 amino acids.
- Top disease associations (Open Targets): ACPA-positive rheumatoid arthritis, blood protein measurement and glomerular filtration rate.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein yippee-like 4 |
|---|---|
| UniProt accession | Q96NS1 |
| Gene | YPEL4 |
| Organism | Homo sapiens |
| Length | 127 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (48)
Diseases linked to this target (Open Targets).
- ACPA-positive rheumatoid arthritis · score 0.10
- blood protein measurement · score 0.10
- glomerular filtration rate · score 0.06
- mean platelet volume · score 0.05
- systolic blood pressure · score 0.04
- cholesterol-ester transfer protein deficiency · score 0.04
- rheumatoid arthritis · score 0.04
- atypical teratoid rhabdoid tumor · score 0.04
- electrocardiography · score 0.03
- aspartate aminotransferase measurement · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96NS1-F1 | alphafold | PREDICTED | 86.88 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96NS1.
Amino-acid sequence (127 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with YPEL4?
The strongest Open Targets associations for YPEL4 are ACPA-positive rheumatoid arthritis, blood protein measurement, glomerular filtration rate, mean platelet volume and systolic blood pressure.
How long is the YPEL4 protein?
The Homo sapiens YPEL4 protein (UniProt Q96NS1) is 127 amino acids long.
Browse: Targets: Y · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96NS1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96NS1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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