Contactin-associated protein-like 3B (CNTNAP3B)
Homo sapiens — UniProt Q96NU0
Data last refreshed: (UniProt release unknown)
Key facts
Contactin-associated protein-like 3B (CNTNAP3B) is a protein from Homo sapiens identified by UniProt accession Q96NU0, 1288 residues long. MolForge cross-references it against 0 known binders and 16 disease associations.
- UniProt accession: Q96NU0; gene symbol CNTNAP3B.
- Organism: Homo sapiens.
- Length: 1288 amino acids.
- Top disease associations (Open Targets): specific language impairment, 7q11.23 microduplication syndrome and Monoamine oxidase A deficiency.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Contactin-associated protein-like 3B |
|---|---|
| UniProt accession | Q96NU0 |
| Gene | CNTNAP3B |
| Organism | Homo sapiens |
| Length | 1288 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (16)
Diseases linked to this target (Open Targets).
- specific language impairment · score 0.09
- 7q11.23 microduplication syndrome · score 0.07
- Monoamine oxidase A deficiency · score 0.07
- microangiopathy and leukoencephalopathy, pontine, autosomal dominant · score 0.05
- Down syndrome · score 0.03
- colorectal cancer · score 0.01
- cutaneous lupus erythematosus · score 0.01
- acute lymphoblastic leukemia · score 0.01
- metopic craniosynostosis · score 0.01
- psoriasis · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96NU0-F1 | alphafold | PREDICTED | 82.97 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96NU0.
Amino-acid sequence (1288 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CNTNAP3B?
The strongest Open Targets associations for CNTNAP3B are specific language impairment, 7q11.23 microduplication syndrome, Monoamine oxidase A deficiency, microangiopathy and leukoencephalopathy, pontine, autosomal dominant and Down syndrome.
How long is the CNTNAP3B protein?
The Homo sapiens CNTNAP3B protein (UniProt Q96NU0) is 1288 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96NU0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96NU0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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