Sterile alpha motif domain-containing protein 11 (SAMD11)
Homo sapiens — UniProt Q96NU1
Data last refreshed: (UniProt release unknown)
Key facts
Sterile alpha motif domain-containing protein 11 (SAMD11) is a protein from Homo sapiens identified by UniProt accession Q96NU1, 681 residues long. MolForge cross-references it against 0 known binders and 34 disease associations.
- UniProt accession: Q96NU1; gene symbol SAMD11.
- Organism: Homo sapiens.
- Length: 681 amino acids.
- Top disease associations (Open Targets): retinitis pigmentosa, mitochondrial DNA measurement and cystatin C measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Sterile alpha motif domain-containing protein 11 |
|---|---|
| UniProt accession | Q96NU1 |
| Gene | SAMD11 |
| Organism | Homo sapiens |
| Length | 681 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (34)
Diseases linked to this target (Open Targets).
- retinitis pigmentosa · score 0.48
- mitochondrial DNA measurement · score 0.20
- cystatin C measurement · score 0.20
- Neutrophil inclusion bodies · score 0.11
- alkaline phosphatase measurement · score 0.06
- attention deficit hyperactivity disorder · score 0.06
- Tourette syndrome · score 0.05
- uncombable hair syndrome · score 0.04
- schizophrenia 15 · score 0.04
- Griscelli syndrome type 3 · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96NU1-F1 | alphafold | PREDICTED | 50.06 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96NU1.
Amino-acid sequence (681 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SAMD11?
The strongest Open Targets associations for SAMD11 are retinitis pigmentosa, mitochondrial DNA measurement, cystatin C measurement, Neutrophil inclusion bodies and alkaline phosphatase measurement.
How long is the SAMD11 protein?
The Homo sapiens SAMD11 protein (UniProt Q96NU1) is 681 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96NU1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96NU1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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