Probable imidazolonepropionase (AMDHD1)
Homo sapiens — UniProt Q96NU7
Data last refreshed: (UniProt release unknown)
Key facts
Probable imidazolonepropionase (AMDHD1) is a protein from Homo sapiens identified by UniProt accession Q96NU7, 426 residues long. MolForge cross-references it against 0 known binders and 39 disease associations.
- UniProt accession: Q96NU7; gene symbol AMDHD1.
- Organism: Homo sapiens.
- Length: 426 amino acids.
- Top disease associations (Open Targets): vitamin D measurement, serum metabolite measurement and cutaneous melanoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Probable imidazolonepropionase |
|---|---|
| UniProt accession | Q96NU7 |
| Gene | AMDHD1 |
| Organism | Homo sapiens |
| Length | 426 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (39)
Diseases linked to this target (Open Targets).
- vitamin D measurement · score 0.29
- serum metabolite measurement · score 0.12
- cutaneous melanoma · score 0.10
- blood metabolite measurement · score 0.08
- amino acid measurement · score 0.08
- protein measurement · score 0.08
- PHF-tau measurement · score 0.06
- Okt4 epitope deficiency · score 0.06
- transient myeloproliferative syndrome · score 0.05
- neutrophil immunodeficiency syndrome · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96NU7-F1 | alphafold | PREDICTED | 96.19 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96NU7.
Amino-acid sequence (426 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with AMDHD1?
The strongest Open Targets associations for AMDHD1 are vitamin D measurement, serum metabolite measurement, cutaneous melanoma, blood metabolite measurement and amino acid measurement.
How long is the AMDHD1 protein?
The Homo sapiens AMDHD1 protein (UniProt Q96NU7) is 426 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96NU7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96NU7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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