Ankyrin repeat domain-containing protein 27 (ANKRD27)
Homo sapiens — UniProt Q96NW4
Data last refreshed: (UniProt release unknown)
Key facts
Ankyrin repeat domain-containing protein 27 (ANKRD27) is a protein from Homo sapiens identified by UniProt accession Q96NW4, 1050 residues long. MolForge cross-references it against 0 known binders and 68 disease associations.
- UniProt accession: Q96NW4; gene symbol ANKRD27.
- Organism: Homo sapiens.
- Length: 1050 amino acids.
- Top disease associations (Open Targets): bradyopsia, systemic lupus erythematosus and mean corpuscular hemoglobin concentration.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ankyrin repeat domain-containing protein 27 |
|---|---|
| UniProt accession | Q96NW4 |
| Gene | ANKRD27 |
| Organism | Homo sapiens |
| Length | 1050 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (68)
Diseases linked to this target (Open Targets).
- bradyopsia · score 0.42
- systemic lupus erythematosus · score 0.27
- mean corpuscular hemoglobin concentration · score 0.26
- mean corpuscular volume · score 0.25
- eosinophilic esophagitis · score 0.21
- PHF-tau measurement · score 0.19
- HbA1c measurement · score 0.18
- mean platelet volume · score 0.17
- mean reticulocyte volume · score 0.16
- mean corpuscular hemoglobin · score 0.15
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96NW4-F1 | alphafold | PREDICTED | 68.31 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96NW4.
Amino-acid sequence (1050 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ANKRD27?
The strongest Open Targets associations for ANKRD27 are bradyopsia, systemic lupus erythematosus, mean corpuscular hemoglobin concentration, mean corpuscular volume and eosinophilic esophagitis.
How long is the ANKRD27 protein?
The Homo sapiens ANKRD27 protein (UniProt Q96NW4) is 1050 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96NW4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96NW4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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