Calcium/calmodulin-dependent protein kinase type 1G (CAMK1G)
Homo sapiens — UniProt Q96NX5
Data last refreshed: (UniProt release unknown)
Key facts
Calcium/calmodulin-dependent protein kinase type 1G (CAMK1G) is a protein from Homo sapiens identified by UniProt accession Q96NX5, 476 residues long. MolForge cross-references it against 7 known binders and 45 disease associations.
- UniProt accession: Q96NX5; gene symbol CAMK1G.
- Organism: Homo sapiens.
- Length: 476 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, Alzheimer disease and multiple sclerosis.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Calcium/calmodulin-dependent protein kinase type 1G |
|---|---|
| UniProt accession | Q96NX5 |
| Gene | CAMK1G |
| Organism | Homo sapiens |
| Length | 476 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (45)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.41
- Alzheimer disease · score 0.35
- multiple sclerosis · score 0.35
- Parkinson disease · score 0.35
- lysosomal storage disease · score 0.35
- amyotrophic lateral sclerosis · score 0.32
- body mass index · score 0.32
- protein measurement · score 0.31
- insulin like growth factor measurement · score 0.27
- adolescent idiopathic scoliosis · score 0.24
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96NX5-F1 | alphafold | PREDICTED | 66.09 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96NX5.
Amino-acid sequence (476 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CAMK1G?
The strongest Open Targets associations for CAMK1G are neurodegenerative disease, Alzheimer disease, multiple sclerosis, Parkinson disease and lysosomal storage disease.
How long is the CAMK1G protein?
The Homo sapiens CAMK1G protein (UniProt Q96NX5) is 476 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96NX5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96NX5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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