Chloride intracellular channel protein 6 (CLIC6)
Homo sapiens — UniProt Q96NY7
Data last refreshed: (UniProt release unknown)
Key facts
Chloride intracellular channel protein 6 (CLIC6) is a protein from Homo sapiens identified by UniProt accession Q96NY7, 704 residues long. MolForge cross-references it against 0 known binders and 100 disease associations.
- UniProt accession: Q96NY7; gene symbol CLIC6.
- Organism: Homo sapiens.
- Length: 704 amino acids.
- Top disease associations (Open Targets): vital capacity, breast carcinoma and atrial fibrillation.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Chloride intracellular channel protein 6 |
|---|---|
| UniProt accession | Q96NY7 |
| Gene | CLIC6 |
| Organism | Homo sapiens |
| Length | 704 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (100)
Diseases linked to this target (Open Targets).
- vital capacity · score 0.49
- breast carcinoma · score 0.39
- atrial fibrillation · score 0.35
- forced expiratory volume · score 0.32
- esophageal carcinoma · score 0.28
- hair shape measurement · score 0.14
- balding measurement · score 0.13
- androgenetic alopecia · score 0.12
- DNA methylation · score 0.12
- myoepithelial tumor · score 0.11
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96NY7-F1 | alphafold | PREDICTED | 58.88 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96NY7.
Amino-acid sequence (704 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CLIC6?
The strongest Open Targets associations for CLIC6 are vital capacity, breast carcinoma, atrial fibrillation, forced expiratory volume and esophageal carcinoma.
How long is the CLIC6 protein?
The Homo sapiens CLIC6 protein (UniProt Q96NY7) is 704 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96NY7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96NY7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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