Forkhead box protein N4 (FOXN4)
Homo sapiens — UniProt Q96NZ1
Data last refreshed: (UniProt release unknown)
Key facts
Forkhead box protein N4 (FOXN4) is a protein from Homo sapiens identified by UniProt accession Q96NZ1, 517 residues long. MolForge cross-references it against 0 known binders and 34 disease associations.
- UniProt accession: Q96NZ1; gene symbol FOXN4.
- Organism: Homo sapiens.
- Length: 517 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, triglyceride measurement and alkaline phosphatase measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Forkhead box protein N4 |
|---|---|
| UniProt accession | Q96NZ1 |
| Gene | FOXN4 |
| Organism | Homo sapiens |
| Length | 517 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (34)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.50
- triglyceride measurement · score 0.20
- alkaline phosphatase measurement · score 0.13
- X-linked retinal dysplasia · score 0.06
- Familial exudative vitreoretinopathy · score 0.05
- choroidal dystrophy, central areolar, 1 · score 0.05
- severe early-childhood-onset retinal dystrophy · score 0.05
- Familial drusen · score 0.04
- X-linked retinoschisis · score 0.04
- retinitis pigmentosa · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96NZ1-F1 | alphafold | PREDICTED | 57.13 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96NZ1.
Amino-acid sequence (517 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FOXN4?
The strongest Open Targets associations for FOXN4 are neurodegenerative disease, triglyceride measurement, alkaline phosphatase measurement, X-linked retinal dysplasia and Familial exudative vitreoretinopathy.
How long is the FOXN4 protein?
The Homo sapiens FOXN4 protein (UniProt Q96NZ1) is 517 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96NZ1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96NZ1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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