WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 1 (WFIKKN1)
Homo sapiens — UniProt Q96NZ8
Data last refreshed: (UniProt release unknown)
Key facts
WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 1 (WFIKKN1) is a protein from Homo sapiens identified by UniProt accession Q96NZ8, 548 residues long. MolForge cross-references it against 0 known binders and 39 disease associations.
- UniProt accession: Q96NZ8; gene symbol WFIKKN1.
- Organism: Homo sapiens.
- Length: 548 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, age at first sexual intercourse measurement and Red cell distribution width.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 1 |
|---|---|
| UniProt accession | Q96NZ8 |
| Gene | WFIKKN1 |
| Organism | Homo sapiens |
| Length | 548 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (39)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.31
- age at first sexual intercourse measurement · score 0.10
- Red cell distribution width · score 0.09
- reticulocyte measurement · score 0.09
- mean corpuscular hemoglobin concentration · score 0.09
- self reported educational attainment · score 0.08
- blood protein measurement · score 0.08
- cystatin C measurement · score 0.06
- serum urea measurement · score 0.05
- autosomal recessive spondylocostal dysostosis · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96NZ8-F1 | alphafold | PREDICTED | 78.09 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96NZ8.
Amino-acid sequence (548 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with WFIKKN1?
The strongest Open Targets associations for WFIKKN1 are neurodegenerative disease, age at first sexual intercourse measurement, Red cell distribution width, reticulocyte measurement and mean corpuscular hemoglobin concentration.
How long is the WFIKKN1 protein?
The Homo sapiens WFIKKN1 protein (UniProt Q96NZ8) is 548 amino acids long.
Browse: Targets: W · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96NZ8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96NZ8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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