RNA-binding protein 14 (RBM14)
Homo sapiens — UniProt Q96PK6
Data last refreshed: (UniProt release unknown)
Key facts
RNA-binding protein 14 (RBM14) is a protein from Homo sapiens identified by UniProt accession Q96PK6, 669 residues long. MolForge cross-references it against 0 known binders and 34 disease associations.
- UniProt accession: Q96PK6; gene symbol RBM14.
- Organism: Homo sapiens.
- Length: 669 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, hypertriglyceridemia 2 and cholesterol-ester transfer protein deficiency.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | RNA-binding protein 14 |
|---|---|
| UniProt accession | Q96PK6 |
| Gene | RBM14 |
| Organism | Homo sapiens |
| Length | 669 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (34)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.45
- hypertriglyceridemia 2 · score 0.07
- cholesterol-ester transfer protein deficiency · score 0.06
- thyroid hormone metabolism, abnormal, 2 · score 0.05
- sitosterolemia · score 0.05
- Combined hyperlipidemia · score 0.05
- homozygous familial hypercholesterolemia · score 0.05
- hypercholesterolemia, autosomal dominant, 3 · score 0.04
- hyperlipidemia due to hepatic triglyceride lipase deficiency · score 0.04
- hypercholesterolemia, autosomal dominant, type B · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96PK6-F1 | alphafold | PREDICTED | 51.66 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96PK6.
Amino-acid sequence (669 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RBM14?
The strongest Open Targets associations for RBM14 are neurodegenerative disease, hypertriglyceridemia 2, cholesterol-ester transfer protein deficiency, thyroid hormone metabolism, abnormal, 2 and sitosterolemia.
How long is the RBM14 protein?
The Homo sapiens RBM14 protein (UniProt Q96PK6) is 669 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96PK6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96PK6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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