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Zinc finger protein 385A (ZNF385A)

Homo sapiens — UniProt Q96PM9

Gene: ZNF385AHomo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Zinc finger protein 385A (ZNF385A) is a protein from Homo sapiens identified by UniProt accession Q96PM9, 386 residues long. MolForge cross-references it against 0 known binders and 101 disease associations.

  • UniProt accession: Q96PM9; gene symbol ZNF385A.
  • Organism: Homo sapiens.
  • Length: 386 amino acids.
  • Top disease associations (Open Targets): ovarian cancer, endometrial cancer and breast adenocarcinoma.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameZinc finger protein 385A
UniProt accessionQ96PM9
GeneZNF385A
OrganismHomo sapiens
Length386 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (101)

Diseases linked to this target (Open Targets).

  • ovarian cancer · score 0.29
  • endometrial cancer · score 0.29
  • breast adenocarcinoma · score 0.28
  • urinary bladder cancer · score 0.28
  • squamous cell lung carcinoma · score 0.28
  • gastric adenocarcinoma · score 0.28
  • esophageal cancer · score 0.28
  • cutaneous melanoma · score 0.25
  • erythrocyte count · score 0.09
  • mean platelet volume · score 0.08

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q96PM9-F1alphafoldPREDICTED61.61—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96PM9.

Amino-acid sequence (386 residues)

MILGSLSRAG PLPLLRQPPI MQPPLDLKQI LPFPLEPAPT LGLFSNYSTM DPVQKAVLSH TFGGPLLKTK RPVISCNICQ IRFNSQSQAE AHYKGNRHAR RVKGIEAAKT RGREPGVREP GDPAPPGSTP TNGDGVAPRP VSMENGLGPA PGSPEKQPGS PSPPSIPETG QGVTKGEGGT PAPASLPGGS KEEEEKAKRL LYCALCKVAV NSLSQLEAHN KGTKHKTILE ARSGLGPIKA YPRLGPPTPG EPEAPAQDRT FHCEICNVKV NSEVQLKQHI SSRRHRDGVA GKPNPLLSRH KKSRGAGELA GTLTFSKELP KSLAGGLLPS PLAVAAVMAA AAGSPLSLRP APAAPLLQGP PITHPLLHPA PGPIRTAHGP ILFSPY

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with ZNF385A?

The strongest Open Targets associations for ZNF385A are ovarian cancer, endometrial cancer, breast adenocarcinoma, urinary bladder cancer and squamous cell lung carcinoma.

How long is the ZNF385A protein?

The Homo sapiens ZNF385A protein (UniProt Q96PM9) is 386 amino acids long.

Browse: Targets: Z · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ96PM9
GeneZNF385A
OrganismHomo sapiens
Length386
Binders0
Diseases101
View on UniProt