Zinc finger protein 385A (ZNF385A)

About Zinc finger protein 385A

Zinc finger protein 385A (ZNF385A) is a protein from Homo sapiens identified by UniProt accession Q96PM9, 386 residues long. MolForge cross-references it against 0 known binders and 101 disease associations.

Target properties

Protein name	Zinc finger protein 385A
UniProt accession	Q96PM9
Gene	ZNF385A
Organism	Homo sapiens
Length	386 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (101)

Diseases linked to this target (Open Targets).

ovarian cancer · score 0.29
endometrial cancer · score 0.29
breast adenocarcinoma · score 0.28
urinary bladder cancer · score 0.28
squamous cell lung carcinoma · score 0.28
gastric adenocarcinoma · score 0.28
esophageal cancer · score 0.28
cutaneous melanoma · score 0.25
erythrocyte count · score 0.09
mean platelet volume · score 0.08

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96PM9-F1	alphafold	PREDICTED	61.61	—

Amino-acid sequence (386 residues)

MILGSLSRAG PLPLLRQPPI MQPPLDLKQI LPFPLEPAPT LGLFSNYSTM DPVQKAVLSH TFGGPLLKTK RPVISCNICQ IRFNSQSQAE AHYKGNRHAR RVKGIEAAKT RGREPGVREP GDPAPPGSTP TNGDGVAPRP VSMENGLGPA PGSPEKQPGS PSPPSIPETG QGVTKGEGGT PAPASLPGGS KEEEEKAKRL LYCALCKVAV NSLSQLEAHN KGTKHKTILE ARSGLGPIKA YPRLGPPTPG EPEAPAQDRT FHCEICNVKV NSEVQLKQHI SSRRHRDGVA GKPNPLLSRH KKSRGAGELA GTLTFSKELP KSLAGGLLPS PLAVAAVMAA AAGSPLSLRP APAAPLLQGP PITHPLLHPA PGPIRTAHGP ILFSPY

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards