Adenylate cyclase type 10 (ADCY10)
Homo sapiens — UniProt Q96PN6
Data last refreshed: (UniProt release unknown)
Key facts
Adenylate cyclase type 10 (ADCY10) is a protein from Homo sapiens identified by UniProt accession Q96PN6, 1610 residues long. MolForge cross-references it against 0 known binders and 423 disease associations.
- UniProt accession: Q96PN6; gene symbol ADCY10.
- Organism: Homo sapiens.
- Length: 1610 amino acids.
- Top disease associations (Open Targets): Idiopathic hypercalciuria, Reduced sperm motility and Abnormal sperm morphology.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Adenylate cyclase type 10 |
|---|---|
| UniProt accession | Q96PN6 |
| Gene | ADCY10 |
| Organism | Homo sapiens |
| Length | 1610 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (423)
Diseases linked to this target (Open Targets).
- Idiopathic hypercalciuria · score 0.52
- Reduced sperm motility · score 0.34
- Abnormal sperm morphology · score 0.34
- sex hormone-binding globulin measurement · score 0.17
- male infertility · score 0.11
- azoospermia · score 0.11
- male infertility with teratozoospermia due to single gene mutation · score 0.10
- schizophrenia · score 0.09
- Male infertility with spermatogenesis disorder due to single gene mutation · score 0.09
- neoplasm · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96PN6-F1 | alphafold | PREDICTED | 81.08 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96PN6.
Amino-acid sequence (1610 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ADCY10?
The strongest Open Targets associations for ADCY10 are Idiopathic hypercalciuria, Reduced sperm motility, Abnormal sperm morphology, sex hormone-binding globulin measurement and male infertility.
How long is the ADCY10 protein?
The Homo sapiens ADCY10 protein (UniProt Q96PN6) is 1610 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96PN6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96PN6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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