KH domain-containing RNA-binding protein QKI (QKI)
Homo sapiens — UniProt Q96PU8
Data last refreshed: (UniProt release unknown)
Key facts
KH domain-containing RNA-binding protein QKI (QKI) is a protein from Homo sapiens identified by UniProt accession Q96PU8, 341 residues long. MolForge cross-references it against 0 known binders and 620 disease associations.
- UniProt accession: Q96PU8; gene symbol QKI.
- Organism: Homo sapiens.
- Length: 341 amino acids.
- Top disease associations (Open Targets): cancer, neurodegenerative disease and hemoglobin measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | KH domain-containing RNA-binding protein QKI |
|---|---|
| UniProt accession | Q96PU8 |
| Gene | QKI |
| Organism | Homo sapiens |
| Length | 341 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (620)
Diseases linked to this target (Open Targets).
- cancer · score 0.56
- neurodegenerative disease · score 0.50
- hemoglobin measurement · score 0.47
- erythrocyte count · score 0.41
- cataract · score 0.40
- body mass index · score 0.38
- platelet component distribution width · score 0.38
- esophageal adenocarcinoma · score 0.37
- gastric carcinoma · score 0.37
- lymphoid neoplasm · score 0.37
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96PU8-F1 | alphafold | PREDICTED | 68.70 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96PU8.
Amino-acid sequence (341 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with QKI?
The strongest Open Targets associations for QKI are cancer, neurodegenerative disease, hemoglobin measurement, erythrocyte count and cataract.
How long is the QKI protein?
The Homo sapiens QKI protein (UniProt Q96PU8) is 341 amino acids long.
Browse: Targets: Q · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96PU8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96PU8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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