Calcium and integrin-binding family member 3 (CIB3)
Homo sapiens — UniProt Q96Q77
Data last refreshed: (UniProt release unknown)
Key facts
Calcium and integrin-binding family member 3 (CIB3) is a protein from Homo sapiens identified by UniProt accession Q96Q77, 187 residues long. MolForge cross-references it against 0 known binders and 24 disease associations.
- UniProt accession: Q96Q77; gene symbol CIB3.
- Organism: Homo sapiens.
- Length: 187 amino acids.
- Top disease associations (Open Targets): neuroinflammatory disorder, mean platelet volume and platelet count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Calcium and integrin-binding family member 3 |
|---|---|
| UniProt accession | Q96Q77 |
| Gene | CIB3 |
| Organism | Homo sapiens |
| Length | 187 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (24)
Diseases linked to this target (Open Targets).
- neuroinflammatory disorder · score 0.26
- mean platelet volume · score 0.13
- platelet count · score 0.12
- age at onset · score 0.06
- Myopia · score 0.06
- cochleosaccular degeneration-cataract syndrome · score 0.05
- Cataract-microcornea syndrome · score 0.04
- lymphocyte count · score 0.04
- monocyte count · score 0.04
- lymphocyte percentage of leukocytes · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96Q77-F1 | alphafold | PREDICTED | 85.06 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96Q77.
Amino-acid sequence (187 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CIB3?
The strongest Open Targets associations for CIB3 are neuroinflammatory disorder, mean platelet volume, platelet count, age at onset and Myopia.
How long is the CIB3 protein?
The Homo sapiens CIB3 protein (UniProt Q96Q77) is 187 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96Q77 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96Q77 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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