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Serine/threonine-protein phosphatase 1 regulatory subunit 10 (PPP1R10)

Homo sapiens — UniProt Q96QC0

Gene: PPP1R10Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Serine/threonine-protein phosphatase 1 regulatory subunit 10 (PPP1R10) is a protein from Homo sapiens identified by UniProt accession Q96QC0, 940 residues long. MolForge cross-references it against 0 known binders and 46 disease associations.

  • UniProt accession: Q96QC0; gene symbol PPP1R10.
  • Organism: Homo sapiens.
  • Length: 940 amino acids.
  • Top disease associations (Open Targets): neurodegenerative disease, Alzheimer disease and Parkinson disease.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameSerine/threonine-protein phosphatase 1 regulatory subunit 10
UniProt accessionQ96QC0
GenePPP1R10
OrganismHomo sapiens
Length940 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (46)

Diseases linked to this target (Open Targets).

  • neurodegenerative disease · score 0.49
  • Alzheimer disease · score 0.46
  • Parkinson disease · score 0.46
  • lysosomal storage disease · score 0.46
  • multiple sclerosis · score 0.46
  • neuroinflammatory disorder · score 0.43
  • monocyte count · score 0.16
  • Delayed speech and language development · score 0.12
  • Intellectual disability, moderate · score 0.12
  • Abnormal facial shape · score 0.12

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q96QC0-F1alphafoldPREDICTED56.90—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96QC0.

Amino-acid sequence (940 residues)

MGSGPIDPKE LLKGLDSFLN RDGEVKSVDG ISKIFSLMKE ARKMVSRCTY LNILLQTRSP EILVKFIDVG GYKLLNNWLT YSKTTNNIPL LQQILLTLQH LPLTVDHLKQ NNTAKLVKQL SKSSEDEELR KLASVLVSDW MAVIRSQSST QPAEKDKKKR KDEGKSRTTL PERPLTEVKA ETRAEEAPEK KREKPKSLRT TAPSHAKFRS TGLELETPSL VPVKKNASTV VVSDKYNLKP IPLKRQSNVA APGDATPPAE KKYKPLNTTP NATKEIKVKI IPPQPMEGLG FLDALNSAPV PGIKIKKKKK VLSPTAAKPS PFEGKTSTEP STAKPSSPEP APPSEAMDAD RPGTPVPPVE VPELMDTASL EPGALDAKPV ESPGDPNQLT RKGRKRKSVT WPEEGKLREY FYFELDETER VNVNKIKDFG EAAKREILSD RHAFETARRL SHDNMEEKVP WVCPRPLVLP SPLVTPGSNS QERYIQAERE KGILQELFLN KESPHEPDPE PYEPIPPKLI PLDEECSMDE TPYVETLEPG GSGGSPDGAG GSKLPPVLAN LMGSMGAGKG PQGPGGGGIN VQEILTSIMG SPNSHPSEEL LKQPDYSDKI KQMLVPHGLL GPGPIANGFP PGGPGGPKGM QHFPPGPGGP MPGPHGGPGG PVGPRLLGPP PPPRGGDPFW DGPGDPMRGG PMRGGPGPGP GPYHRGRGGR GGNEPPPPPP PFRGARGGRS GGGPPNGRGG PGGGMVGGGG HRPHEGPGGG MGNSSGHRPH EGPGGGMGSG HRPHEGPGGS MGGGGGHRPH EGPGGGISGG SGHRPHEGPG GGMGAGGGHR PHEGPGGSMG GSGGHRPHEG PGHGGPHGHR PHDVPGHRGH DHRGPPPHEH RGHDGPGHGG GGHRGHDGGH SHGGDMSNRP VCRHFMMKGN CRYENNCAFY HPGVNGPPLP

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with PPP1R10?

The strongest Open Targets associations for PPP1R10 are neurodegenerative disease, Alzheimer disease, Parkinson disease, lysosomal storage disease and multiple sclerosis.

How long is the PPP1R10 protein?

The Homo sapiens PPP1R10 protein (UniProt Q96QC0) is 940 amino acids long.

Browse: Targets: P · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ96QC0
GenePPP1R10
OrganismHomo sapiens
Length940
Binders0
Diseases46
View on UniProt