DEP domain-containing protein 7 (DEPDC7)
Homo sapiens — UniProt Q96QD5
Data last refreshed: (UniProt release unknown)
Key facts
DEP domain-containing protein 7 (DEPDC7) is a protein from Homo sapiens identified by UniProt accession Q96QD5, 511 residues long. MolForge cross-references it against 0 known binders and 28 disease associations.
- UniProt accession: Q96QD5; gene symbol DEPDC7.
- Organism: Homo sapiens.
- Length: 511 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, autism and platelet component distribution width.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | DEP domain-containing protein 7 |
|---|---|
| UniProt accession | Q96QD5 |
| Gene | DEPDC7 |
| Organism | Homo sapiens |
| Length | 511 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (28)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.46
- autism · score 0.12
- platelet component distribution width · score 0.08
- heel bone mineral density · score 0.08
- hepatocellular carcinoma · score 0.08
- forced expiratory volume · score 0.05
- cystatin C measurement · score 0.05
- vital capacity · score 0.05
- sleep measurement · score 0.02
- sex hormone-binding globulin measurement · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96QD5-F1 | alphafold | PREDICTED | 73.63 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96QD5.
Amino-acid sequence (511 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DEPDC7?
The strongest Open Targets associations for DEPDC7 are neurodegenerative disease, autism, platelet component distribution width, heel bone mineral density and hepatocellular carcinoma.
How long is the DEPDC7 protein?
The Homo sapiens DEPDC7 protein (UniProt Q96QD5) is 511 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96QD5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96QD5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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