Sodium-coupled neutral amino acid symporter 2 (SLC38A2)
Homo sapiens — UniProt Q96QD8
Data last refreshed: (UniProt release unknown)
Key facts
Sodium-coupled neutral amino acid symporter 2 (SLC38A2) is a protein from Homo sapiens identified by UniProt accession Q96QD8, 506 residues long. MolForge cross-references it against 0 known binders and 133 disease associations.
- UniProt accession: Q96QD8; gene symbol SLC38A2.
- Organism: Homo sapiens.
- Length: 506 amino acids.
- Top disease associations (Open Targets): lean body mass, appendicular lean mass and body height.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Sodium-coupled neutral amino acid symporter 2 |
|---|---|
| UniProt accession | Q96QD8 |
| Gene | SLC38A2 |
| Organism | Homo sapiens |
| Length | 506 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (133)
Diseases linked to this target (Open Targets).
- lean body mass · score 0.51
- appendicular lean mass · score 0.46
- body height · score 0.45
- fat body mass · score 0.44
- hair color · score 0.36
- body weight · score 0.36
- eosinophil count · score 0.35
- whole body water mass · score 0.35
- base metabolic rate measurement · score 0.34
- grip strength measurement · score 0.34
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96QD8-F1 | alphafold | PREDICTED | 79.09 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96QD8.
Amino-acid sequence (506 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SLC38A2?
The strongest Open Targets associations for SLC38A2 are lean body mass, appendicular lean mass, body height, fat body mass and hair color.
How long is the SLC38A2 protein?
The Homo sapiens SLC38A2 protein (UniProt Q96QD8) is 506 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96QD8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96QD8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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