Small integral membrane protein 14 (SMIM14)
Homo sapiens — UniProt Q96QK8
Data last refreshed: (UniProt release unknown)
Key facts
Small integral membrane protein 14 (SMIM14) is a protein from Homo sapiens identified by UniProt accession Q96QK8, 99 residues long. MolForge cross-references it against 0 known binders and 23 disease associations.
- UniProt accession: Q96QK8; gene symbol SMIM14.
- Organism: Homo sapiens.
- Length: 99 amino acids.
- Top disease associations (Open Targets): body height, neutrophil count and triglyceride measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Small integral membrane protein 14 |
|---|---|
| UniProt accession | Q96QK8 |
| Gene | SMIM14 |
| Organism | Homo sapiens |
| Length | 99 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (23)
Diseases linked to this target (Open Targets).
- body height · score 0.39
- neutrophil count · score 0.32
- triglyceride measurement · score 0.27
- neurofibrillary tangles measurement · score 0.26
- appendicular lean mass · score 0.12
- neutrophil percentage of leukocytes · score 0.08
- self reported educational attainment · score 0.08
- metabolite measurement · score 0.04
- platelet component distribution width · score 0.03
- serum gamma-glutamyl transferase measurement · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96QK8-F1 | alphafold | PREDICTED | 62.76 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96QK8.
Amino-acid sequence (99 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SMIM14?
The strongest Open Targets associations for SMIM14 are body height, neutrophil count, triglyceride measurement, neurofibrillary tangles measurement and appendicular lean mass.
How long is the SMIM14 protein?
The Homo sapiens SMIM14 protein (UniProt Q96QK8) is 99 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96QK8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96QK8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.