Serine/threonine-protein kinase H2 (PSKH2)
Homo sapiens — UniProt Q96QS6
Data last refreshed: (UniProt release unknown)
Key facts
Serine/threonine-protein kinase H2 (PSKH2) is a protein from Homo sapiens identified by UniProt accession Q96QS6, 385 residues long. MolForge cross-references it against 0 known binders and 14 disease associations.
- UniProt accession: Q96QS6; gene symbol PSKH2.
- Organism: Homo sapiens.
- Length: 385 amino acids.
- Top disease associations (Open Targets): neutrophil count, adolescent idiopathic scoliosis and neurodegenerative disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Serine/threonine-protein kinase H2 |
|---|---|
| UniProt accession | Q96QS6 |
| Gene | PSKH2 |
| Organism | Homo sapiens |
| Length | 385 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (14)
Diseases linked to this target (Open Targets).
- neutrophil count · score 0.37
- adolescent idiopathic scoliosis · score 0.29
- neurodegenerative disease · score 0.27
- myeloid white cell count · score 0.26
- leukocyte count · score 0.25
- total cholesterol measurement · score 0.15
- self reported educational attainment · score 0.13
- cognitive function measurement · score 0.11
- mathematical ability · score 0.11
- total blood protein measurement · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96QS6-F1 | alphafold | PREDICTED | 81.80 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96QS6.
Amino-acid sequence (385 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PSKH2?
The strongest Open Targets associations for PSKH2 are neutrophil count, adolescent idiopathic scoliosis, neurodegenerative disease, myeloid white cell count and leukocyte count.
How long is the PSKH2 protein?
The Homo sapiens PSKH2 protein (UniProt Q96QS6) is 385 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96QS6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96QS6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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