1-aminocyclopropane-1-carboxylate synthase-like protein 1 (ACCS)
Homo sapiens — UniProt Q96QU6
Data last refreshed: (UniProt release unknown)
Key facts
1-aminocyclopropane-1-carboxylate synthase-like protein 1 (ACCS) is a protein from Homo sapiens identified by UniProt accession Q96QU6, 501 residues long. MolForge cross-references it against 0 known binders and 46 disease associations.
- UniProt accession: Q96QU6; gene symbol ACCS.
- Organism: Homo sapiens.
- Length: 501 amino acids.
- Top disease associations (Open Targets): IGA glomerulonephritis, pulse pressure measurement and systolic blood pressure.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | 1-aminocyclopropane-1-carboxylate synthase-like protein 1 |
|---|---|
| UniProt accession | Q96QU6 |
| Gene | ACCS |
| Organism | Homo sapiens |
| Length | 501 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (46)
Diseases linked to this target (Open Targets).
- IGA glomerulonephritis · score 0.29
- pulse pressure measurement · score 0.15
- systolic blood pressure · score 0.12
- serum alanine aminotransferase measurement · score 0.04
- body fat percentage · score 0.04
- bone density · score 0.04
- urate measurement · score 0.04
- high density lipoprotein cholesterol measurement · score 0.04
- sex hormone-binding globulin measurement · score 0.04
- aspartate aminotransferase measurement · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96QU6-F1 | alphafold | PREDICTED | 86.11 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96QU6.
Amino-acid sequence (501 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ACCS?
The strongest Open Targets associations for ACCS are IGA glomerulonephritis, pulse pressure measurement, systolic blood pressure, serum alanine aminotransferase measurement and body fat percentage.
How long is the ACCS protein?
The Homo sapiens ACCS protein (UniProt Q96QU6) is 501 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96QU6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96QU6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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