Exportin-6 (XPO6)
Homo sapiens — UniProt Q96QU8
Data last refreshed: (UniProt release unknown)
Key facts
Exportin-6 (XPO6) is a protein from Homo sapiens identified by UniProt accession Q96QU8, 1125 residues long. MolForge cross-references it against 0 known binders and 37 disease associations.
- UniProt accession: Q96QU8; gene symbol XPO6.
- Organism: Homo sapiens.
- Length: 1125 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, leukocyte count and lymphocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Exportin-6 |
|---|---|
| UniProt accession | Q96QU8 |
| Gene | XPO6 |
| Organism | Homo sapiens |
| Length | 1125 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (37)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.50
- leukocyte count · score 0.27
- lymphocyte count · score 0.26
- alkaline phosphatase measurement · score 0.26
- apolipoprotein A 1 measurement · score 0.25
- monocyte count · score 0.22
- mathematical ability · score 0.20
- myeloid white cell count · score 0.17
- self reported educational attainment · score 0.15
- PHF-tau measurement · score 0.15
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96QU8-F1 | alphafold | PREDICTED | 86.62 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96QU8.
Amino-acid sequence (1125 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with XPO6?
The strongest Open Targets associations for XPO6 are neurodegenerative disease, leukocyte count, lymphocyte count, alkaline phosphatase measurement and apolipoprotein A 1 measurement.
How long is the XPO6 protein?
The Homo sapiens XPO6 protein (UniProt Q96QU8) is 1125 amino acids long.
Browse: Targets: X · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96QU8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96QU8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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