Histone H2A type 1-A (H2AC1)
Homo sapiens — UniProt Q96QV6
Data last refreshed: (UniProt release unknown)
Key facts
Histone H2A type 1-A (H2AC1) is a protein from Homo sapiens identified by UniProt accession Q96QV6, 131 residues long. MolForge cross-references it against 0 known binders and 29 disease associations.
- UniProt accession: Q96QV6; gene symbol H2AC1.
- Organism: Homo sapiens.
- Length: 131 amino acids.
- Top disease associations (Open Targets): viral disease, infectious disease and diabetes mellitus.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Histone H2A type 1-A |
|---|---|
| UniProt accession | Q96QV6 |
| Gene | H2AC1 |
| Organism | Homo sapiens |
| Length | 131 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (29)
Diseases linked to this target (Open Targets).
- viral disease · score 0.50
- infectious disease · score 0.50
- diabetes mellitus · score 0.11
- sex hormone-binding globulin measurement · score 0.11
- mathematical ability · score 0.11
- diabetic maculopathy · score 0.11
- mean corpuscular volume · score 0.11
- waist-hip ratio · score 0.09
- serum albumin measurement · score 0.08
- diabetic retinopathy · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96QV6-F1 | alphafold | PREDICTED | 90.72 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96QV6.
Amino-acid sequence (131 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with H2AC1?
The strongest Open Targets associations for H2AC1 are viral disease, infectious disease, diabetes mellitus, sex hormone-binding globulin measurement and mathematical ability.
How long is the H2AC1 protein?
The Homo sapiens H2AC1 protein (UniProt Q96QV6) is 131 amino acids long.
Browse: Targets: H · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96QV6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96QV6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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