Pannexin-3 (PANX3)
Homo sapiens — UniProt Q96QZ0
Data last refreshed: (UniProt release unknown)
Key facts
Pannexin-3 (PANX3) is a protein from Homo sapiens identified by UniProt accession Q96QZ0, 392 residues long. MolForge cross-references it against 0 known binders and 32 disease associations.
- UniProt accession: Q96QZ0; gene symbol PANX3.
- Organism: Homo sapiens.
- Length: 392 amino acids.
- Top disease associations (Open Targets): schizophrenia, neoplasm and osteoarthritis.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Pannexin-3 |
|---|---|
| UniProt accession | Q96QZ0 |
| Gene | PANX3 |
| Organism | Homo sapiens |
| Length | 392 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (32)
Diseases linked to this target (Open Targets).
- schizophrenia · score 0.11
- neoplasm · score 0.08
- osteoarthritis · score 0.06
- atrial fibrillation · score 0.05
- chondrocalcinosis 2 · score 0.04
- Angel-shaped phalango-epiphyseal dysplasia · score 0.03
- glycoprotein storage disease · score 0.03
- talo-patello-scaphoid osteolysis · score 0.03
- Camptodactyly-arthropathy-coxa-vara-pericarditis syndrome · score 0.03
- carcinoma · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96QZ0-F1 | alphafold | PREDICTED | 81.72 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96QZ0.
Amino-acid sequence (392 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PANX3?
The strongest Open Targets associations for PANX3 are schizophrenia, neoplasm, osteoarthritis, atrial fibrillation and chondrocalcinosis 2.
How long is the PANX3 protein?
The Homo sapiens PANX3 protein (UniProt Q96QZ0) is 392 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96QZ0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96QZ0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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