Zinc finger protein 300 (ZNF300)
Homo sapiens — UniProt Q96RE9
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger protein 300 (ZNF300) is a protein from Homo sapiens identified by UniProt accession Q96RE9, 604 residues long. MolForge cross-references it against 0 known binders and 55 disease associations.
- UniProt accession: Q96RE9; gene symbol ZNF300.
- Organism: Homo sapiens.
- Length: 604 amino acids.
- Top disease associations (Open Targets): inflammatory bowel disease, ulcerative colitis and Crohn's disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger protein 300 |
|---|---|
| UniProt accession | Q96RE9 |
| Gene | ZNF300 |
| Organism | Homo sapiens |
| Length | 604 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (55)
Diseases linked to this target (Open Targets).
- inflammatory bowel disease · score 0.14
- ulcerative colitis · score 0.14
- Crohn's disease · score 0.08
- neoplasm · score 0.08
- acute myeloid leukemia · score 0.08
- non-small cell lung carcinoma · score 0.07
- lung cancer · score 0.05
- hepatocellular carcinoma · score 0.04
- cancer · score 0.04
- ankylosing spondylitis · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96RE9-F1 | alphafold | PREDICTED | 68.32 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96RE9.
Amino-acid sequence (604 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZNF300?
The strongest Open Targets associations for ZNF300 are inflammatory bowel disease, ulcerative colitis, Crohn's disease, neoplasm and acute myeloid leukemia.
How long is the ZNF300 protein?
The Homo sapiens ZNF300 protein (UniProt Q96RE9) is 604 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96RE9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96RE9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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