Tumor necrosis factor receptor superfamily member 13C (TNFRSF13C)
Homo sapiens — UniProt Q96RJ3
Data last refreshed: (UniProt release unknown)
Key facts
Tumor necrosis factor receptor superfamily member 13C (TNFRSF13C) is a protein from Homo sapiens identified by UniProt accession Q96RJ3, 184 residues long. MolForge cross-references it against 0 known binders and 394 disease associations.
- UniProt accession: Q96RJ3; gene symbol TNFRSF13C.
- Organism: Homo sapiens.
- Length: 184 amino acids.
- Top disease associations (Open Targets): immunodeficiency, common variable, 4, recurrent infections associated with rare immunoglobulin isotypes deficiency and common variable immunodeficiency.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Tumor necrosis factor receptor superfamily member 13C |
|---|---|
| UniProt accession | Q96RJ3 |
| Gene | TNFRSF13C |
| Organism | Homo sapiens |
| Length | 184 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (394)
Diseases linked to this target (Open Targets).
- immunodeficiency, common variable, 4 · score 0.64
- recurrent infections associated with rare immunoglobulin isotypes deficiency · score 0.43
- common variable immunodeficiency · score 0.40
- Sjogren syndrome · score 0.37
- blood protein measurement · score 0.30
- autoimmune thrombocytopenic purpura · score 0.29
- lupus nephritis · score 0.26
- Anemia, Hemolytic, Autoimmune · score 0.26
- coronary artery disease · score 0.16
- total blood protein measurement · score 0.15
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96RJ3-F1 | alphafold | PREDICTED | 63.02 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96RJ3.
Amino-acid sequence (184 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TNFRSF13C?
The strongest Open Targets associations for TNFRSF13C are immunodeficiency, common variable, 4, recurrent infections associated with rare immunoglobulin isotypes deficiency, common variable immunodeficiency, Sjogren syndrome and blood protein measurement.
How long is the TNFRSF13C protein?
The Homo sapiens TNFRSF13C protein (UniProt Q96RJ3) is 184 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96RJ3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96RJ3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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