Endoplasmic reticulum-Golgi intermediate compartment protein 2 (ERGIC2)
Homo sapiens — UniProt Q96RQ1
Data last refreshed: (UniProt release unknown)
Key facts
Endoplasmic reticulum-Golgi intermediate compartment protein 2 (ERGIC2) is a protein from Homo sapiens identified by UniProt accession Q96RQ1, 377 residues long. MolForge cross-references it against 0 known binders and 55 disease associations.
- UniProt accession: Q96RQ1; gene symbol ERGIC2.
- Organism: Homo sapiens.
- Length: 377 amino acids.
- Top disease associations (Open Targets): body height, appendicular lean mass and triglyceride measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Endoplasmic reticulum-Golgi intermediate compartment protein 2 |
|---|---|
| UniProt accession | Q96RQ1 |
| Gene | ERGIC2 |
| Organism | Homo sapiens |
| Length | 377 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (55)
Diseases linked to this target (Open Targets).
- body height · score 0.42
- appendicular lean mass · score 0.37
- triglyceride measurement · score 0.37
- protein measurement · score 0.33
- alkaline phosphatase measurement · score 0.30
- heel bone mineral density · score 0.30
- vital capacity · score 0.29
- total cholesterol measurement · score 0.29
- vascular endothelial growth factor C measurement · score 0.29
- blood protein measurement · score 0.28
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96RQ1-F1 | alphafold | PREDICTED | 81.03 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96RQ1.
Amino-acid sequence (377 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ERGIC2?
The strongest Open Targets associations for ERGIC2 are body height, appendicular lean mass, triglyceride measurement, protein measurement and alkaline phosphatase measurement.
How long is the ERGIC2 protein?
The Homo sapiens ERGIC2 protein (UniProt Q96RQ1) is 377 amino acids long.
Browse: Targets: E · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96RQ1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96RQ1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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