L-amino-acid oxidase (IL4I1)
Homo sapiens — UniProt Q96RQ9
Data last refreshed: (UniProt release unknown)
Key facts
L-amino-acid oxidase (IL4I1) is a protein from Homo sapiens identified by UniProt accession Q96RQ9, 567 residues long. MolForge cross-references it against 0 known binders and 135 disease associations.
- UniProt accession: Q96RQ9; gene symbol IL4I1.
- Organism: Homo sapiens.
- Length: 567 amino acids.
- Top disease associations (Open Targets): familial infantile bilateral striatal necrosis, infantile bilateral striatal necrosis and neurodegenerative disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | L-amino-acid oxidase |
|---|---|
| UniProt accession | Q96RQ9 |
| Gene | IL4I1 |
| Organism | Homo sapiens |
| Length | 567 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (135)
Diseases linked to this target (Open Targets).
- familial infantile bilateral striatal necrosis · score 0.38
- infantile bilateral striatal necrosis · score 0.38
- neurodegenerative disease · score 0.32
- age at menopause · score 0.14
- neoplasm · score 0.10
- cancer · score 0.09
- lung adenocarcinoma · score 0.09
- mean corpuscular hemoglobin · score 0.08
- hepatocellular carcinoma · score 0.08
- 7q11.23 microduplication syndrome · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96RQ9-F1 | alphafold | PREDICTED | 86.29 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96RQ9.
Amino-acid sequence (567 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with IL4I1?
The strongest Open Targets associations for IL4I1 are familial infantile bilateral striatal necrosis, infantile bilateral striatal necrosis, neurodegenerative disease, age at menopause and neoplasm.
How long is the IL4I1 protein?
The Homo sapiens IL4I1 protein (UniProt Q96RQ9) is 567 amino acids long.
Browse: Targets: I · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96RQ9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96RQ9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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