Formin-binding protein 1 (FNBP1)
Homo sapiens — UniProt Q96RU3
Data last refreshed: (UniProt release unknown)
Key facts
Formin-binding protein 1 (FNBP1) is a protein from Homo sapiens identified by UniProt accession Q96RU3, 617 residues long. MolForge cross-references it against 0 known binders and 146 disease associations.
- UniProt accession: Q96RU3; gene symbol FNBP1.
- Organism: Homo sapiens.
- Length: 617 amino acids.
- Top disease associations (Open Targets): optic cup area measurement, lung adenocarcinoma and gastric adenocarcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Formin-binding protein 1 |
|---|---|
| UniProt accession | Q96RU3 |
| Gene | FNBP1 |
| Organism | Homo sapiens |
| Length | 617 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (146)
Diseases linked to this target (Open Targets).
- optic cup area measurement · score 0.30
- lung adenocarcinoma · score 0.20
- gastric adenocarcinoma · score 0.20
- anemia · score 0.19
- protein measurement · score 0.19
- acute myeloid leukemia · score 0.19
- breast ductal adenocarcinoma · score 0.19
- non-small cell lung carcinoma · score 0.19
- metabolite measurement · score 0.19
- urinary bladder carcinoma · score 0.19
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96RU3-F1 | alphafold | PREDICTED | 78.33 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96RU3.
Amino-acid sequence (617 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FNBP1?
The strongest Open Targets associations for FNBP1 are optic cup area measurement, lung adenocarcinoma, gastric adenocarcinoma, anemia and protein measurement.
How long is the FNBP1 protein?
The Homo sapiens FNBP1 protein (UniProt Q96RU3) is 617 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96RU3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96RU3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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