BTB/POZ domain-containing protein KCTD15 (KCTD15)
Homo sapiens — UniProt Q96SI1
Data last refreshed: (UniProt release unknown)
Key facts
BTB/POZ domain-containing protein KCTD15 (KCTD15) is a protein from Homo sapiens identified by UniProt accession Q96SI1, 283 residues long. MolForge cross-references it against 0 known binders and 63 disease associations.
- UniProt accession: Q96SI1; gene symbol KCTD15.
- Organism: Homo sapiens.
- Length: 283 amino acids.
- Top disease associations (Open Targets): body mass index, lean body mass and body weight.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | BTB/POZ domain-containing protein KCTD15 |
|---|---|
| UniProt accession | Q96SI1 |
| Gene | KCTD15 |
| Organism | Homo sapiens |
| Length | 283 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (63)
Diseases linked to this target (Open Targets).
- body mass index · score 0.51
- lean body mass · score 0.48
- body weight · score 0.46
- physical activity measurement · score 0.46
- smoking behavior · score 0.40
- fat body mass · score 0.39
- nose morphology measurement · score 0.32
- brain measurement · score 0.32
- facial morphology measurement · score 0.32
- whole body water mass · score 0.31
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96SI1-F1 | alphafold | PREDICTED | 82.17 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96SI1.
Amino-acid sequence (283 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with KCTD15?
The strongest Open Targets associations for KCTD15 are body mass index, lean body mass, body weight, physical activity measurement and smoking behavior.
How long is the KCTD15 protein?
The Homo sapiens KCTD15 protein (UniProt Q96SI1) is 283 amino acids long.
Browse: Targets: K · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96SI1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96SI1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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