Cytochrome P450 2S1 (CYP2S1)

About Cytochrome P450 2S1

Cytochrome P450 2S1 (CYP2S1) is a protein from Homo sapiens identified by UniProt accession Q96SQ9, 504 residues long. MolForge cross-references it against 0 known binders and 54 disease associations.

Target properties

Protein name	Cytochrome P450 2S1
UniProt accession	Q96SQ9
Gene	CYP2S1
Organism	Homo sapiens
Length	504 residues
Molecular weight	—
EC numbers	—
Target class	—
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (54)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.45
Nasal Cavity Polyp · score 0.34
heel bone mineral density · score 0.28
neutrophil count · score 0.27
leukocyte count · score 0.26
cutaneous melanoma · score 0.23
glioblastoma multiforme · score 0.18
endometrial cancer · score 0.11
lung adenocarcinoma · score 0.10
myeloid white cell count · score 0.10

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96SQ9-F1	alphafold	PREDICTED	92.62	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96SQ9.

Amino-acid sequence (504 residues)

MEATGTWALL LALALLLLLT LALSGTRARG HLPPGPTPLP LLGNLLQLRP GALYSGLMRL SKKYGPVFTI YLGPWRPVVV LVGQEAVREA LGGQAEEFSG RGTVAMLEGT FDGHGVFFSN GERWRQLRKF TMLALRDLGM GKREGEELIQ AEARCLVETF QGTEGRPFDP SLLLAQATSN VVCSLLFGLR FSYEDKEFQA VVRAAGGTLL GVSSQGGQTY EMFSWFLRPL PGPHKQLLHH VSTLAAFTVR QVQQHQGNLD ASGPARDLVD AFLLKMAQEE QNPGTEFTNK NMLMTVIYLL FAGTMTVSTT VGYTLLLLMK YPHVQKWVRE ELNRELGAGQ APSLGDRTRL PYTDAVLHEA QRLLALVPMG IPRTLMRTTR FRGYTLPQGT EVFPLLGSIL HDPNIFKHPE EFNPDRFLDA DGRFRKHEAF LPFSLGKRVC LGEGLAKAEL FLFFTTILQA FSLESPCPPD TLSLKPTVSG LFNIPPAFQL QVRPTDLHST TQTR

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards