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Oxysterol-binding protein-related protein 9 (OSBPL9)

Homo sapiens — UniProt Q96SU4

Gene: OSBPL9Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Oxysterol-binding protein-related protein 9 (OSBPL9) is a protein from Homo sapiens identified by UniProt accession Q96SU4, 736 residues long. MolForge cross-references it against 0 known binders and 27 disease associations.

  • UniProt accession: Q96SU4; gene symbol OSBPL9.
  • Organism: Homo sapiens.
  • Length: 736 amino acids.
  • Top disease associations (Open Targets): PHF-tau measurement, vitamin K-dependent protein C measurement and lymphocyte count.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameOxysterol-binding protein-related protein 9
UniProt accessionQ96SU4
GeneOSBPL9
OrganismHomo sapiens
Length736 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (27)

Diseases linked to this target (Open Targets).

  • PHF-tau measurement · score 0.23
  • vitamin K-dependent protein C measurement · score 0.19
  • lymphocyte count · score 0.15
  • endocrine system disease · score 0.08
  • lymphocyte percentage of leukocytes · score 0.05
  • hyperparathyroidism · score 0.03
  • Red cell distribution width · score 0.03
  • parathyroid disease · score 0.02
  • cerebral infarction · score 0.01
  • neoplasm · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q96SU4-F1alphafoldPREDICTED75.88—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96SU4.

Amino-acid sequence (736 residues)

MASIMEGPLS KWTNVMKGWQ YRWFVLDYNA GLLSYYTSKD KMMRGSRRGC VRLRGAVIGI DDEDDSTFTI TVDQKTFHFQ ARDADEREKW IHALEETILR HTLQLQGLDS GFVPSVQDFD KKLTEADAYL QILIEQLKLF DDKLQNCKED EQRKKIETLK ETTNSMVESI KHCIVLLQIA KDQSNAEKHA DGMISTINPV DAIYQPSPLE PVISTMPSQT VLPPEPVQLC KSEQRPSSLP VGPVLATLGH HQTPTPNSTG SGHSPPSSSL TSPSHVNLSP NTVPEFSYSS SEDEFYDADE FHQSGSSPKR LIDSSGSASV LTHSSSGNSL KRPDTTESLN SSLSNGTSDA DLFDSHDDRD DDAEAGSVEE HKSVIMHLLS QVRLGMDLTK VVLPTFILER RSLLEMYADF FAHPDLFVSI SDQKDPKDRM VQVVKWYLSA FHAGRKGSVA KKPYNPILGE IFQCHWTLPN DTEENTELVS EGPVPWVSKN SVTFVAEQVS HHPPISAFYA ECFNKKIQFN AHIWTKSKFL GMSIGVHNIG QGCVSCLDYD EHYILTFPNG YGRSILTVPW VELGGECNIN CSKTGYSANI IFHTKPFYGG KKHRITAEIF SPNDKKSFCS IEGEWNGVMY AKYATGENTV FVDTKKLPII KKKVRKLEDQ NEYESRSLWK DVTFNLKIRD IDAATEAKHR LEERQRAEAR ERKEKEIQWE TRLFHEDGEC WVYDEPLLKR LGAAKH

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with OSBPL9?

The strongest Open Targets associations for OSBPL9 are PHF-tau measurement, vitamin K-dependent protein C measurement, lymphocyte count, endocrine system disease and lymphocyte percentage of leukocytes.

How long is the OSBPL9 protein?

The Homo sapiens OSBPL9 protein (UniProt Q96SU4) is 736 amino acids long.

Browse: Targets: O · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ96SU4
GeneOSBPL9
OrganismHomo sapiens
Length736
Binders0
Diseases27
View on UniProt