Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 (NMNAT3)

About Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3

Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 (NMNAT3) is a protein from Homo sapiens identified by UniProt accession Q96T66, 252 residues long. MolForge cross-references it against 0 known binders and 240 disease associations.

Target properties

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Disease associations (240)

Diseases linked to this target (Open Targets).

• substance abuse · score 0.27
• antisocial behaviour measurement · score 0.27
• attention deficit hyperactivity disorder · score 0.27
• gut microbiome measurement · score 0.18
• Blackfan-Diamond anemia · score 0.07
• beta-thalassemia-X-linked thrombocytopenia syndrome · score 0.06
• dehydrated hereditary stomatocytosis · score 0.06
• hereditary persistence of fetal hemoglobin-sickle cell disease syndrome · score 0.06
• Familial hemophagocytic lymphohistiocytosis · score 0.06
• Congenital dyserythropoietic anemia type I · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96T66.

Amino-acid sequence (252 residues)

External references