Insulinoma-associated protein 2 (INSM2)
Homo sapiens — UniProt Q96T92
Data last refreshed: (UniProt release unknown)
Key facts
Insulinoma-associated protein 2 (INSM2) is a protein from Homo sapiens identified by UniProt accession Q96T92, 566 residues long. MolForge cross-references it against 0 known binders and 51 disease associations.
- UniProt accession: Q96T92; gene symbol INSM2.
- Organism: Homo sapiens.
- Length: 566 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, hemoglobin measurement and erythrocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Insulinoma-associated protein 2 |
|---|---|
| UniProt accession | Q96T92 |
| Gene | INSM2 |
| Organism | Homo sapiens |
| Length | 566 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (51)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.53
- hemoglobin measurement · score 0.10
- erythrocyte count · score 0.10
- hematocrit · score 0.09
- monocyte count · score 0.09
- alkaline phosphatase measurement · score 0.08
- red blood cell density measurement · score 0.08
- mean corpuscular hemoglobin · score 0.08
- body height · score 0.07
- lean body mass · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96T92-F1 | alphafold | PREDICTED | 55.13 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96T92.
Amino-acid sequence (566 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with INSM2?
The strongest Open Targets associations for INSM2 are neurodegenerative disease, hemoglobin measurement, erythrocyte count, hematocrit and monocyte count.
How long is the INSM2 protein?
The Homo sapiens INSM2 protein (UniProt Q96T92) is 566 amino acids long.
Browse: Targets: I · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96T92 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96T92 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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