Dehydrogenase/reductase SDR family member 9 (DHRS9)

About Dehydrogenase/reductase SDR family member 9

Dehydrogenase/reductase SDR family member 9 (DHRS9) is a protein from Homo sapiens identified by UniProt accession Q9BPW9, 319 residues long. MolForge cross-references it against 0 known binders and 121 disease associations.

Target properties

Protein name	Dehydrogenase/reductase SDR family member 9
UniProt accession	Q9BPW9
Gene	DHRS9
Organism	Homo sapiens
Length	319 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Approved drugs hitting this target (2)

DrugCentral-linked approved drugs that act on this protein.

Disease associations (121)

Diseases linked to this target (Open Targets).

C-reactive protein measurement · score 0.42
serum gamma-glutamyl transferase measurement · score 0.41
alkaline phosphatase measurement · score 0.39
serum alanine aminotransferase measurement · score 0.39
urate measurement · score 0.33
apolipoprotein A 1 measurement · score 0.33
Red cell distribution width · score 0.32
Intrahepatic cholestasis of pregnancy · score 0.27
triglyceride measurement · score 0.26
mean corpuscular hemoglobin concentration · score 0.15

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BPW9-F1	alphafold	PREDICTED	94.55	—

Amino-acid sequence (319 residues)

MLFWVLGLLI LCGFLWTRKG KLKIEDITDK YIFITGCDSG FGNLAARTFD KKGFHVIAAC LTESGSTALK AETSERLRTV LLDVTDPENV KRTAQWVKNQ VGEKGLWGLI NNAGVPGVLA PTDWLTLEDY REPIEVNLFG LISVTLNMLP LVKKAQGRVI NVSSVGGRLA IVGGGYTPSK YAVEGFNDSL RRDMKAFGVH VSCIEPGLFK TNLADPVKVI EKKLAIWEQL SPDIKQQYGE GYIEKSLDKL KGNKSYVNMD LSPVVECMDH ALTSLFPKTH YAAGKDAKIF WIPLSHMPAA LQDFLLLKQK AELANPKAV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards