Dehydrogenase/reductase SDR family member 9 (DHRS9)
Homo sapiens — UniProt Q9BPW9
Data last refreshed: (UniProt release unknown)
Key facts
Dehydrogenase/reductase SDR family member 9 (DHRS9) is a protein from Homo sapiens identified by UniProt accession Q9BPW9, 319 residues long. MolForge cross-references it against 2 known binders and 121 disease associations.
- UniProt accession: Q9BPW9; gene symbol DHRS9.
- Organism: Homo sapiens.
- Length: 319 amino acids.
- Top disease associations (Open Targets): C-reactive protein measurement, serum gamma-glutamyl transferase measurement and alkaline phosphatase measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Dehydrogenase/reductase SDR family member 9 |
|---|---|
| UniProt accession | Q9BPW9 |
| Gene | DHRS9 |
| Organism | Homo sapiens |
| Length | 319 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (121)
Diseases linked to this target (Open Targets).
- C-reactive protein measurement · score 0.42
- serum gamma-glutamyl transferase measurement · score 0.41
- alkaline phosphatase measurement · score 0.39
- serum alanine aminotransferase measurement · score 0.39
- urate measurement · score 0.33
- apolipoprotein A 1 measurement · score 0.33
- Red cell distribution width · score 0.32
- Intrahepatic cholestasis of pregnancy · score 0.27
- triglyceride measurement · score 0.26
- mean corpuscular hemoglobin concentration · score 0.15
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BPW9-F1 | alphafold | PREDICTED | 94.55 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BPW9.
Amino-acid sequence (319 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DHRS9?
The strongest Open Targets associations for DHRS9 are C-reactive protein measurement, serum gamma-glutamyl transferase measurement, alkaline phosphatase measurement, serum alanine aminotransferase measurement and urate measurement.
How long is the DHRS9 protein?
The Homo sapiens DHRS9 protein (UniProt Q9BPW9) is 319 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BPW9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BPW9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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