L-fucose dehydrogenase (HSD17B14)
Homo sapiens — UniProt Q9BPX1
Data last refreshed: (UniProt release unknown)
Key facts
L-fucose dehydrogenase (HSD17B14) is a protein from Homo sapiens identified by UniProt accession Q9BPX1, 270 residues long. MolForge cross-references it against 0 known binders and 101 disease associations.
- UniProt accession: Q9BPX1; gene symbol HSD17B14.
- Organism: Homo sapiens.
- Length: 270 amino acids.
- Top disease associations (Open Targets): blood protein measurement, pathological myopia and Myopia.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | L-fucose dehydrogenase |
|---|---|
| UniProt accession | Q9BPX1 |
| Gene | HSD17B14 |
| Organism | Homo sapiens |
| Length | 270 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (101)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.29
- pathological myopia · score 0.11
- Myopia · score 0.11
- head and neck squamous cell carcinoma · score 0.11
- azoospermia · score 0.08
- partial chromosome Y deletion · score 0.07
- male infertility with teratozoospermia due to single gene mutation · score 0.06
- congenital bilateral absence of vas deferens · score 0.05
- spermatogenic failure 25 · score 0.05
- spermatogenic failures 50 · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BPX1-F1 | alphafold | PREDICTED | 96.54 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BPX1.
Amino-acid sequence (270 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with HSD17B14?
The strongest Open Targets associations for HSD17B14 are blood protein measurement, pathological myopia, Myopia, head and neck squamous cell carcinoma and azoospermia.
How long is the HSD17B14 protein?
The Homo sapiens HSD17B14 protein (UniProt Q9BPX1) is 270 amino acids long.
Browse: Targets: H · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BPX1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BPX1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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