ATP-dependent RNA helicase DDX50 (DDX50)
Homo sapiens — UniProt Q9BQ39
Data last refreshed: (UniProt release unknown)
Key facts
ATP-dependent RNA helicase DDX50 (DDX50) is a protein from Homo sapiens identified by UniProt accession Q9BQ39, 737 residues long. MolForge cross-references it against 0 known binders and 16 disease associations.
- UniProt accession: Q9BQ39; gene symbol DDX50.
- Organism: Homo sapiens.
- Length: 737 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, Familial prostate cancer and prostate cancer.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | ATP-dependent RNA helicase DDX50 |
|---|---|
| UniProt accession | Q9BQ39 |
| Gene | DDX50 |
| Organism | Homo sapiens |
| Length | 737 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (16)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.31
- Familial prostate cancer · score 0.11
- prostate cancer · score 0.11
- prostate carcinoma · score 0.11
- cortical thickness · score 0.05
- eosinophil count · score 0.05
- platelet component distribution width · score 0.04
- testosterone measurement · score 0.03
- infect · score 0.01
- infection · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BQ39-F1 | alphafold | PREDICTED | 72.88 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BQ39.
Amino-acid sequence (737 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DDX50?
The strongest Open Targets associations for DDX50 are neurodegenerative disease, Familial prostate cancer, prostate cancer, prostate carcinoma and cortical thickness.
How long is the DDX50 protein?
The Homo sapiens DDX50 protein (UniProt Q9BQ39) is 737 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BQ39 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BQ39 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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