Methylosome protein WDR77 (WDR77)
Homo sapiens — UniProt Q9BQA1
Data last refreshed: (UniProt release unknown)
Key facts
Methylosome protein WDR77 (WDR77) is a protein from Homo sapiens identified by UniProt accession Q9BQA1, 342 residues long. MolForge cross-references it against 0 known binders and 46 disease associations.
- UniProt accession: Q9BQA1; gene symbol WDR77.
- Organism: Homo sapiens.
- Length: 342 amino acids.
- Top disease associations (Open Targets): endometrial cancer, clear cell renal carcinoma and urinary bladder cancer.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Methylosome protein WDR77 |
|---|---|
| UniProt accession | Q9BQA1 |
| Gene | WDR77 |
| Organism | Homo sapiens |
| Length | 342 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (46)
Diseases linked to this target (Open Targets).
- endometrial cancer · score 0.18
- clear cell renal carcinoma · score 0.18
- urinary bladder cancer · score 0.13
- neurodegenerative disease · score 0.12
- triple-negative breast cancer · score 0.07
- cancer · score 0.07
- t-tau:beta-amyloid 1-42 ratio measurement · score 0.05
- viral disease · score 0.03
- cryopyrin-associated periodic syndrome · score 0.03
- neoplasm · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BQA1-F1 | alphafold | PREDICTED | 91.03 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BQA1.
Amino-acid sequence (342 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with WDR77?
The strongest Open Targets associations for WDR77 are endometrial cancer, clear cell renal carcinoma, urinary bladder cancer, neurodegenerative disease and triple-negative breast cancer.
How long is the WDR77 protein?
The Homo sapiens WDR77 protein (UniProt Q9BQA1) is 342 amino acids long.
Browse: Targets: W · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BQA1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BQA1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.