Histone H4 transcription factor (HINFP)
Homo sapiens — UniProt Q9BQA5
Data last refreshed: (UniProt release unknown)
Key facts
Histone H4 transcription factor (HINFP) is a protein from Homo sapiens identified by UniProt accession Q9BQA5, 517 residues long. MolForge cross-references it against 0 known binders and 45 disease associations.
- UniProt accession: Q9BQA5; gene symbol HINFP.
- Organism: Homo sapiens.
- Length: 517 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, Parkinson disease and multiple sclerosis.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Histone H4 transcription factor |
|---|---|
| UniProt accession | Q9BQA5 |
| Gene | HINFP |
| Organism | Homo sapiens |
| Length | 517 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (45)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.53
- Parkinson disease · score 0.37
- multiple sclerosis · score 0.37
- lysosomal storage disease · score 0.37
- Alzheimer disease · score 0.37
- reticulocyte count · score 0.15
- mean corpuscular hemoglobin concentration · score 0.11
- calcium measurement · score 0.09
- sex hormone-binding globulin measurement · score 0.09
- HbA1c measurement · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BQA5-F1 | alphafold | PREDICTED | 70.99 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BQA5.
Amino-acid sequence (517 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with HINFP?
The strongest Open Targets associations for HINFP are neurodegenerative disease, Parkinson disease, multiple sclerosis, lysosomal storage disease and Alzheimer disease.
How long is the HINFP protein?
The Homo sapiens HINFP protein (UniProt Q9BQA5) is 517 amino acids long.
Browse: Targets: H · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BQA5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BQA5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.