Cytochrome b-245 chaperone 1 (CYBC1)
Homo sapiens — UniProt Q9BQA9
Data last refreshed: (UniProt release unknown)
Key facts
Cytochrome b-245 chaperone 1 (CYBC1) is a protein from Homo sapiens identified by UniProt accession Q9BQA9, 187 residues long. MolForge cross-references it against 0 known binders and 34 disease associations.
- UniProt accession: Q9BQA9; gene symbol CYBC1.
- Organism: Homo sapiens.
- Length: 187 amino acids.
- Top disease associations (Open Targets): granulomatous disease, chronic, autosomal recessive, 5, chronic granulomatous disease and inflammatory bowel disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Cytochrome b-245 chaperone 1 |
|---|---|
| UniProt accession | Q9BQA9 |
| Gene | CYBC1 |
| Organism | Homo sapiens |
| Length | 187 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (34)
Diseases linked to this target (Open Targets).
- granulomatous disease, chronic, autosomal recessive, 5 · score 0.51
- chronic granulomatous disease · score 0.38
- inflammatory bowel disease · score 0.10
- platelet count · score 0.06
- glycogen storage disease VI · score 0.03
- hepatocellular carcinoma · score 0.02
- infection · score 0.02
- infect · score 0.02
- metastatic melanoma · score 0.01
- ovarian carcinoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BQA9-F1 | alphafold | PREDICTED | 83.19 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BQA9.
Amino-acid sequence (187 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CYBC1?
The strongest Open Targets associations for CYBC1 are granulomatous disease, chronic, autosomal recessive, 5, chronic granulomatous disease, inflammatory bowel disease, platelet count and glycogen storage disease VI.
How long is the CYBC1 protein?
The Homo sapiens CYBC1 protein (UniProt Q9BQA9) is 187 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BQA9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BQA9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.