Tubulin alpha-1C chain (TUBA1C)
Homo sapiens — UniProt Q9BQE3
Data last refreshed: (UniProt release unknown)
Key facts
Tubulin alpha-1C chain (TUBA1C) is a protein from Homo sapiens identified by UniProt accession Q9BQE3, 449 residues long. MolForge cross-references it against 0 known binders and 164 disease associations.
- UniProt accession: Q9BQE3; gene symbol TUBA1C.
- Organism: Homo sapiens.
- Length: 449 amino acids.
- Top disease associations (Open Targets): viral disease, neurodegenerative disease and lung cancer.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Tubulin alpha-1C chain |
|---|---|
| UniProt accession | Q9BQE3 |
| Gene | TUBA1C |
| Organism | Homo sapiens |
| Length | 449 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (164)
Diseases linked to this target (Open Targets).
- viral disease · score 0.46
- neurodegenerative disease · score 0.41
- lung cancer · score 0.37
- breast cancer · score 0.37
- neoplasm · score 0.37
- malignant epithelial tumor of ovary · score 0.37
- fallopian tube neoplasm · score 0.37
- peritoneal neoplasm · score 0.37
- non-small cell lung carcinoma · score 0.37
- neutropenia · score 0.34
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BQE3-F1 | alphafold | PREDICTED | 91.50 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BQE3.
Amino-acid sequence (449 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TUBA1C?
The strongest Open Targets associations for TUBA1C are viral disease, neurodegenerative disease, lung cancer, breast cancer and neoplasm.
How long is the TUBA1C protein?
The Homo sapiens TUBA1C protein (UniProt Q9BQE3) is 449 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BQE3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BQE3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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