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Selenoprotein S (SELENOS)

Homo sapiens — UniProt Q9BQE4

Gene: SELENOSHomo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Selenoprotein S (SELENOS) is a protein from Homo sapiens identified by UniProt accession Q9BQE4, 189 residues long. MolForge cross-references it against 0 known binders and 276 disease associations.

  • UniProt accession: Q9BQE4; gene symbol SELENOS.
  • Organism: Homo sapiens.
  • Length: 189 amino acids.
  • Top disease associations (Open Targets): body height, type 2 diabetes mellitus and triple-negative breast cancer.

Target properties

Protein nameSelenoprotein S
UniProt accessionQ9BQE4
GeneSELENOS
OrganismHomo sapiens
Length189 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (276)

Diseases linked to this target (Open Targets).

  • body height · score 0.09
  • type 2 diabetes mellitus · score 0.09
  • triple-negative breast cancer · score 0.08
  • cancer · score 0.07
  • episodic ataxia type 7 · score 0.07
  • Charcot-Marie-Tooth disease type 1D · score 0.06
  • myopathy, tubular aggregate, 2 · score 0.05
  • Arteritis · score 0.05
  • hematocrit · score 0.05
  • peripheral arterial disease · score 0.05

3D Structure

Predicted structure for Q9BQE4 is available from the AlphaFold Protein Structure Database.

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BQE4.

Amino-acid sequence (189 residues)

MERQEESLSA RPALETEGLR FLHTTVGSLL ATYGWYIVFS CILLYVVFQK LSARLRALRQ RQLDRAAAAV EPDVVVKRQE ALAAARLKMQ EELNAQVEKH KEKLKQLEEE KRRQKIEMWD SMQEGKSYKG NAKKPQEEDS PGPSTSSVLK RKSDRKPLRG GGYNPLSGEG GGACSWRPGR RGPSSGGUG

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with SELENOS?

The strongest Open Targets associations for SELENOS are body height, type 2 diabetes mellitus, triple-negative breast cancer, cancer and episodic ataxia type 7.

How long is the SELENOS protein?

The Homo sapiens SELENOS protein (UniProt Q9BQE4) is 189 amino acids long.

Browse: Targets: S · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9BQE4
GeneSELENOS
OrganismHomo sapiens
Length189
Binders0
Diseases276
View on UniProt